Summary: This review presents a thorough investigation of the role of CD47 in gastrointestinal cancers.We performed a comprehensive, in-depth review of over 100 preclinical and clinical studies focused on inhibiting CD47.The research highlights the pliers potential of targeted CD47 to enhance existing treatments by boosting the immune response to c
It is well consensus among researchers that the non-Newtonian fluid equipped in closed enclosures brings complicated mathematical models and hence one cannot examine flow field truly.The present attempt is first numerical investigation to evaluate the buoyantly convective non-Newtonian fluid flow equipped in hexagonal shaped cavity.The uniformly he
Tumor microenvironments Wax stick are rich in extracellular nucleotides that can be metabolized by ectoenzymes to produce adenosine, a nucleoside involved in controlling immune responses.Multiple myeloma, a plasma cell malignancy developed within a bone marrow niche, exploits adenosinergic pathways to customize the immune homeostasis of the tumor.C
Abstract Background Those attempting to implement changes in health care settings often find that Wax stick intervention efforts do not progress as expected.Unexpected outcomes are often attributed to variation and/or error in implementation processes.We argue that some unanticipated variation in intervention outcomes arises because unexpected conv
Automatic analysis of colocalizing biological structures in multi-channel fluorescence microscopy images is an important task calm to quantify and understand biological processes at high spatial-temporal resolution.Here, we introduce a software suite for colocalization analysis of spot-like objects in multi-channel fluorescence microscopy images.Th